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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT3 All Species: 22.73
Human Site: Y110 Identified Species: 41.67
UniProt: O60678 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60678 NP_005779.1 531 59903 Y110 V E Y M N S I Y N P V P W E K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092890 531 59784 Y110 V E Y M N S I Y N P V P W E K
Dog Lupus familis XP_534089 541 60618 Y120 V E Y M N S I Y N P V P W E K
Cat Felis silvestris
Mouse Mus musculus Q922H1 532 59884 Y108 V E Y M N S I Y N P V P W E K
Rat Rattus norvegicus O70467 528 59401 Y108 V E Y M N S I Y N P V P W D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505718 571 63850 C150 V A Y M N S L C N P V P W E K
Chicken Gallus gallus XP_420907 526 59430 S108 P A Y L N S L S S P L P W D G
Frog Xenopus laevis Q8AV13 369 42306
Zebra Danio Brachydanio rerio Q5RGQ2 419 48204 K30 E Q Q Q Q K H K Q P Q H Q Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396035 525 60169 Y109 K T W E S E E Y L R P V I E D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192186 519 58632 D111 K P E V P W A D D C Y M K P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82210 366 41153
Baker's Yeast Sacchar. cerevisiae P38074 348 39768
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.1 90.9 N.A. 89.8 89.2 N.A. 78.8 70.8 35.4 35.7 N.A. N.A. 42.5 N.A. 45
Protein Similarity: 100 N.A. 96.8 95.1 N.A. 93.9 93.9 N.A. 85.9 83.2 49.1 52.3 N.A. N.A. 62.5 N.A. 63.6
P-Site Identity: 100 N.A. 100 100 N.A. 100 93.3 N.A. 80 40 0 6.6 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 86.6 73.3 0 26.6 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 33.1 31.2 N.A.
Protein Similarity: N.A. N.A. N.A. 48.2 43.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 8 0 0 0 0 16 8 % D
% Glu: 8 39 8 8 0 8 8 0 0 0 0 0 0 47 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 39 0 0 0 0 0 8 0 0 % I
% Lys: 16 0 0 0 0 8 0 8 0 0 0 0 8 0 47 % K
% Leu: 0 0 0 8 0 0 16 0 8 0 8 0 0 0 0 % L
% Met: 0 0 0 47 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 54 0 0 0 47 0 0 0 0 0 0 % N
% Pro: 8 8 0 0 8 0 0 0 0 62 8 54 0 8 0 % P
% Gln: 0 8 8 8 8 0 0 0 8 0 8 0 8 8 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 54 0 8 8 0 0 0 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 47 0 0 8 0 0 0 0 0 0 47 8 0 0 8 % V
% Trp: 0 0 8 0 0 8 0 0 0 0 0 0 54 0 0 % W
% Tyr: 0 0 54 0 0 0 0 47 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _